Research Scientist, CRI

Research Scientist, Mouse Genome Engineering Core

Why UT Southwestern Medical Center?

With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. At UT Southwestern, we invest in you with opportunities for career growth and development that align with your future goals and help to provide security for you and your family. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more that are all available on the day you start work. UT Southwestern is honored to be a Veteran Friendly work environment that is home to approximately 800 veterans. We value your integrity, dedication, and the commitment you’ve made to our country. We’re proud to support your next mission. Ranked by Forbes as one of the Top 10 National Employers, we invite you to be a part of the UT Southwestern team where you’ll discover teamwork, professionalism, and consistent opportunities for growth.

Children’s Research Institute

The Children’s Research Institute (CRI) at UT Southwestern has an exciting opportunity for a Research Scientist to lead the Mouse Genome Engineering Core. Our core generates novel mouse genetic models for the CRI and the broader scientific community. The mission of the core is to 1) use CRISPR methods to generate novel mouse models and 2) to perform research to advance in vivo gene editing technologies. The core’s faculty director is Dr. Hao Zhu, Professor in CRI.

We are seeking a highly skilled scientist with expertise in molecular biology and genetics and the potential to lead a core with an ambitious scientific mission. The Research Scientist will work with members of our scientific community to design and generate new genetically engineered mouse models. We have made over 230 new strains and we will continue serve the community in this way. The Research Scientist will be responsible for the design, execution, and management of transgenic mouse creation. This work primarily requires performing CRISPR/Cas9 knockout and knockin experiments in mouse embryos.

Additional responsibilities include communicating with clients, maintaining records, interpreting and analyzing data, and managing facility equipment and supplies. Besides assisting with the daily operations of the core, there will be the opportunity to develop a research program that creates and utilizes new transgenic technologies. Transgenic or microinjection experience is not required, and advanced training will be offered. Molecular biology experience and strong scientific skills are highly preferred. This would be an ideal position for someone who is interested in leading a core with a cutting edge biomedical research mission.

Preferred Qualifications

• Advanced degree (Ph.D. or equivalent) 
• Experience in molecular biology, biochemistry, biotechnology, or genetics
• Effective people skills

Experience and Education

• Ph.D. degree with major coursework in field of assignment and five (5) years research experience in field of assignment, including at least two (2) years at level of Senior Research Associate or equivalent. or
• Master’s degree with major coursework in field of assignment and seven (7) years research experience in field of assignment, including at least three (3) years at level of Senior Research Associate or equivalent. or
• Bachelor’s degree with major coursework in field of assignment and nine (9) years research experience in field of assignment, including at least four (4) years at level of Senior Research Associate or equivalent.

Lab Duties

• Design, troubleshooting, and project management for transgenic mouse creation.
• Maintain a transgenic project database for recordkeeping and for research.
• Educate and communicate with clients on individual projects.
• Perform research to advance CRISPR and other transgenic technologies.
• Perform microinjection in mouse zygotes.

Job Duties

• Plans, organizes, coordinates, directs, and personally participates in assigned scientific or medical research projects.
• Selects or assists in selection of key research personnel.
• Determines specific goals or objectives to be attained and assigns and reviews work of subordinates.
• Plans experimental protocols.
• Reviews and analyzes resulting research data.
• Revises techniques or approaches to work problems as indicated necessary by research data.
• Compiles, writes, and submits research results to supervisor.
• Prepares or assists in preparation of research papers, reports, and abstracts for publication as one of co-authors.
• Designs, develops, or adapts equipment used in experiments or research to obtain desired results.
• Plans and supervises training of technicians and other laboratory personnel with respect to proper laboratory techniques, use of laboratory equipment, and safety procedures.
• May confer with industrial, governmental, or other groups concerning progress or results of research project.
• Performs other duties as assigned.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/

This position is security-sensitive and subject to Texas Education Code §51.215, which authorizes UT Southwestern to obtain criminal history record information. UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

To learn more, please visit: https://jobs.utsouthwestern.edu/why-work-here/diversity-inclusion